Farfarello were developed at some point prior to the Queen Zenobia Incident, created through infecting Hunters with t-Abyss Virus. In 2005, BSAA chief Clive R. O'Brian provided a pack of Farfarello for Il Veltro, a small paramilitary named after the 2004 Italian movement. The group lost control of their pack at their base in Valkoinen Mökki Airport, resulting in a plane crash and the loss of all ground forces. This also resulted in the crashing of a cargo plane that Chris Redfield and Jessica Sherawat witnessed, due to one of the Farfarello being sucked into the engine while it was attacking it. Later on, the Farfarello were encountered by BSAA officers dispatched to the area.